All Questions page - 563

The two arms of adaptive immunity are antibody-mediated immunity, which operates through the production of the proteins called _______, and cell-mediated immunity, which works through the production of cells that destroy infected _______ in the body. The central cells of antibody-mediated immunity are known as _______ cells, while the central cells of cell-mediated immunity are known as _______ cells.

An antibody is an immune system protein that can bind to a particular _______. Antibodies are seen in two forms: as receptors on the surface of _______ cells and as free-standing proteins that are _______ by these cells.

The cells of both antibody-mediated and cell-mediated immunity exist in great numbers in nodes of the body’s fluid- drainage network, the _______.

A B cell that has become activated against a given microbe divides rapidly to produce clones of two types of daughter cells: _______ cells, which produce the antibodies that will directly fight the invader, and _______ cells, which will remain in the body long after the infection has passed.

T cells specific to a given invader become activated by binding to a cell whose central function is to initiate adaptive immunity by displaying microbial antigens. These are the _______ cells, the most important of which is the _______ cell.

AIDS is devastating to the immune system because the virus that causes it has, as its primary target, the _______ cells that are central to both cell- and antibody-mediated immunity.

Toll-like receptors are the primary _______ of microbial infection in the human body and also serve to ______ both the innate and adaptive immune responses.

Invading microbes can be ingested whole by various members of the class of immune system cells known as ______.

An antigen is any substance that _______.

The human body’s first line of defense against invading pathogens is not the immune system, but rather a set of physical ______ to infection, the most important of which is .

The innate immune response will target any object in the body perceived to be _____, while the adaptive immune response targets ______.

When smallpox raged in England in the 18th century, most of its victims were young children. Meanwhile, the people least likely to die from it were senior citizens. Why should this have been so?

An antigen is:

a. any immune system protein.

b. any substance that elicits an immune system response.

c. any cell that functions in the immune system response.

d. the ultimate product of a vaccination.

e. a particular land of lymphocyte.

Public health officials agree that, since the 1960s, asthma has been increasing among children in developed countries such as the United States. Among the tentative explanations for this increase is the “hygiene hypothesis,” which holds that the problem is that many children are growing up in environments that are “pristine”—very clean and devoid of household pets. What could the linkage be between an immune system condition such as asthma and growing up in a pristine environment?

The pathogens that the immune system fights generally are (select all that apply):

a. poisons.

b. living things.

c. microbes.

d. produced by the body itself.

e. fungi, bacteria, or viruses.

All T and B cells begin development in the ______, but T cells complete development in the ______.

a. lymphatic network; bone marrow

b. lungs; pancreas

c. pancreas; thymus

d. bone marrow; thymus

e. lymphatic network; thymus